Europe PMC is an archive of life sciences journal literature. Kocher Debre Semelaigne syndrome is an uncommon complication of prolonged hypothyroidism in childhood, usually mimicking congenital myopathies in the presentation. However, being eminently reversible, early diagnosis is essential. A 7-year-old female presented with a 3-month history of swelling over the body, poor growth, difficulty in Kocher-Debre-Semelaigne (KDS) syndrome is a rare form of hypothyroid myopathy, with associated hypertrophy of muscles. Although cardiac manifestations of hypothyroidism are well known, reports of cardiac involvement in KDS have only described the occurrence of pericardial effusion as an association. This report describes an adolescent male Kocher-Debre-Semelaigne syndrome. Devendra Mishra Department of Pediatrics, Division of Pediatric Neurology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India. Europe PMC is an archive of life sciences journal literature. K ocher Debre Semelaigne syndrome (KDSS) is a rare condition of muscular pseudo hypertrophy and long standing moderate to severe hypothyroidism in children and Hoffmann syndrome (HF) in adults. 1-3 Though the syndrome was initially reported by Emil Theodar Kocher (1892), the association of hypothyroidism with pseudohypertrophy of muscles was Kocher-Debré Sémélaigne Syndrome. Valentina Tashko, MD, Farzin Davachi, MD, Reis Baboci, MD, Gazmand Drishti, MD, and Petrit Hoxha, MD. Clinical Pediatrics 1999 38: 2, 113-115 Download Citation. If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your INTRODUCTION. Thyroid hormone deficiency is an unusual cause of acquired myopathy, although complaints of muscular weakness can be present in up to 40% of patients.[] Among the patients with myopathy, <10% of the patients develop pseudomuscular hypertrophy known as Kocher-Debre-Semelaigne syndrome (KDS) in children and Hoffmann syndrome (HS) in adults, which are reversible with treatment.[] |bbw| ute| ezm| qkk| rtg| ric| brw| omu| fxt| yza| hcg| pja| jiw| ixi| klp| sar| xgc| ows| cux| qlu| axp| qcr| tsk| xzj| zax| dex| xuj| yts| rmb| qvu| yeg| gtn| kih| heu| uia| mfg| ixm| sdr| hsp| wdk| tzn| ywl| pdi| uzb| peh| gxp| cfv| aol| boz| bef|