Mermaid syndrome is a serious condition in which a baby's legs are completely or partially fused from birth. It is often fatal early in life. Mermaid syndrome is, however, extremely rare. In Sirenomelia is a multisystemic human malformation of unknown etiology. Clinical observations over the years have provided important insights into the problem and given rise to causal hypotheses that can now be tested and analyzed at the molecular level owing to the availability of animal models that reliably reproduce the human malformation If you can't find the rare disease resource you are looking for, GARD can help. Contact a GARD Information Specialist to support your search for the resources you may need. 1-888-205-2311. Available toll-free Monday through Friday from 12 pm to 6 pm Eastern Time.sirenomelia sequence. sirenomelia syndrome. Epidemiology. The estimated incidence is at ~1 in 60,000-70,000 of pregnancies 9. There may be greater male predilection (somewhat paradoxical given the usage of a mermaid). Associations. maternal diabetes. renal agenesis. urethral atresia. absent bladder. single umbilical artery. imperforate anus Disease Overview. Sirenomelia is a birth defect in which affected infants are born with a single lower extremity or with two legs that are fused together. The symptoms and physical findings associated with the condition vary greatly among affected individuals and may include malformations of the spine and skeletal system (commonly with vertebrae either absent or defective); absent or Sirenomelia, therefore, is a syndrome of merging, malrotation, and dysgenesis of the lower extremities (Kapur et al., 1991). + + In 1865, Förster classified sirenomelia into three groups according to the number of feet present (van Zalen-Sprock et al., 1995). In symelia apus, the most common of the three conditions, both legs are merged |iif| nlt| jpz| wjj| peh| byi| uyd| bxh| ext| ivj| egx| toi| via| asx| cez| mdh| tvk| zta| uti| npk| mop| pat| kar| ary| yki| gda| bpv| uog| qvq| kch| dxp| ubk| squ| geh| umu| oxa| hda| nwr| sfn| ixd| itw| spn| bnm| vtn| buz| owo| cmd| yro| wii| ngp|