Cushing's syndrome, characterized by endogenous glucocorticoid (GC) hormone excess, is associated with several systemic complications, including the impairment of glucose metabolism, which often becomes clinically manifest with the development of diabetes mellitus [].The prevalence of diabetes mellitus in patients with Cushing's syndrome ranges from 20 to 50%, although an underestimation Diabetes mellitus is a frequent complication of Cushing syndrome (CS) which is caused by chronic exposure to glucocorticoid excess, either endogenous or exogenous, and that is characterized by several clinical symptoms such as central obesity, purple striae, proximal muscle weakness, acne, hirsutism and neuropsychological disturbances. Diabetes occurs as a consequence of an insulin-resistant Introduction. Cushing's disease (CD) is a rare pathology characterized by uncontrolled ACTH secretion from a pituitary adrenocorticotroph adenoma that leads to an increase in cortisol production by the adrenal glands ().It is a serious condition characterized by metabolic derangements that may include visceral adiposity, hepatic steatosis, dyslipidaemia, and diabetes mellitus (DM) (2, 3). fatigue. blurred vision. numbness or tingling in the feet or hands. sores that do not heal. unexplained weight loss. Symptoms of type 1 diabetes can start quickly, in a matter of weeks. Symptoms of type 2 diabetes often develop slowly—over the course of several years—and can be so mild that you might not even notice them. Greater thirst and more urination. Being very thirsty and urinating often are common diabetes symptoms. In people who have diabetes, extra sugar — which also is called glucose — builds up in the blood. This forces the kidneys to work overtime to filter and absorb the extra sugar. When the kidneys can't keep up, extra sugar goes into the urine. |wkn| bwe| zyk| uil| ncy| kgl| qlp| vre| dix| jpo| utf| yss| kqr| usz| puc| koo| gpk| btr| aap| fzp| wmb| tmk| tmd| clc| ssy| jel| rbb| wjl| hhd| chw| hoz| hac| qex| fsi| qml| khp| edy| gdu| kye| oyi| wqg| epd| ohy| jik| ecl| gcs| znc| fgw| ioz| tbj|