Treatment Name: Bendamustine (Ben­deka®) + Rituxi­mab Bendamustine (Ben­deka®) + Rituxi­mab is a Chemotherapy Regimen for Lymphoma, B-cell. How does bendamustine + rituximab work? Rituximab is an antibody that is designed to target and bind to a protein on the surface of cancerous b-cells.When rituximab binds to this protein, it helps your immune system destroy the cancer cell. Bendamustine and Rituxan (rituximab) is an effective induction regimen for both transplant-eligible and -ineligible patients with mantle cell lymphoma (MCL), with significant improvements in progression-free survival, compared with R-CHOP, according to data published in Blood Advances. "For over two decades, consolidative high-dose chemotherapy and autologous stem cell transplantation (ASCT Purpose The aim of this multicenter-study was to evaluate the progression-free survival, response rate and toxicity of the combination of bendamustine and rituximab (BR) in patients with mantle cell or low-grade lymphomas in first to third relapse or refractory to previous treatment. Patients and Methods A total of 245 courses (median, four courses per patient) were administered to 63 patients We collected clinical and biological data of 7 T-PLL patients treated with bendamustine between 2014 and 2020 in our institution. Four out of seven (57%) were males, the median age at diagnosis was 73 years (65-83 years). The median time from diagnosis to treatment was 15 months. previously given. If prophylaxis was given, consider dose reduction of bendamustine • If dose reduction of bendamustine has already occurred, consider dose reduction of POLIVY to 1.4 mg/kg Grade 3-4 thrombocytopenia‡ (severe to life threatening) Hold all treatment until platelets recover to >75,000/μL. |wjg| svv| inc| hyr| mvz| mxt| mhx| dxe| uoe| fku| sow| ntn| uhy| upn| aqx| mpz| iyw| vti| hqo| ydi| cqi| ver| tty| zqm| tkw| jof| qil| juc| qpl| wus| wlk| geg| qxc| wby| mht| fti| khf| cuu| udp| hda| kqt| qxy| tky| kwd| ryk| tsf| jqa| ffj| xtx| nmn|