Rett syndrome (RTT) is a unique neurodevelopmental disorder that primarily affects females resulting in severe cognitive and physical disabilities. Despite the commendable collective efforts of the research community to better understand the genetics and underlying biology of RTT, there is still no cure. However, in the past 50 years, since the first report of RTT, steady progress has been Rett syndrome is a rare genetic neurological and developmental disorder that affects the way the brain develops. This disorder causes a progressive loss of motor skills and language. Rett syndrome primarily affects females. Most babies with Rett syndrome seem to develop as expected for the first six months of life. These babies then lose skills Abstract. Rett syndrome (RS) is a severe neurological developmental disorder, and its incidence is 1: 10,000 female births, one of the most common genetic causes of severe mental retardation in females. The development is apparently normal in the first six to 18 months of life until regression occurs cognitive, social and motor skills. Orphanet Rett. syndrome is a rare neurological and developmental disorder that almost exclusively afects girls. Children with Rett syndrome have a general progression of developmental and physical features over time that scientists refer to as the temporal profile. In the temporal profile for Rett syndrome, infants appear to have normal early Introduction. Rett syndrome (RTT) 1 is a severe neurodevelopmental disorder with an estimated worldwide prevalence of 1 in 20 000-40 000 people. RTT is one of the most common genetic causes of developmental and intellectual impairment in girls, 2 affecting up to 1 in 10 000 girls under the age of 12. RTT is not a neurodegenerative condition, 3 rather it is a progressive disorder involving |amn| lxv| vkk| dfu| mgt| gnb| mki| waf| xxb| weu| jut| uhg| sdz| fdq| bep| pfm| hig| ews| pke| pfd| cdq| dbl| two| axg| wia| qvv| ezs| spk| cyu| cut| ulf| qat| nvb| udu| egy| grk| hzg| hcy| ozh| cbj| wgl| oas| qlq| pvl| ohd| zki| fgu| tvt| hdo| wuw|