This study was undertaken to determine whether use of the direct renin inhibitor aliskiren would reduce cardiovascular and renal events in patients with type 2 diabetes and chronic kidney disease aliskiren. ALTITUDE will determine whether dual RAAS blockade with the direct renin inhibitor aliskiren in combination with an ACEi or ARB will reduce major morbidity and mortality in a broad range of high-risk patients with type 2 diabetes. OBJECTIVE—To assess the cost-effectiveness of intensive versus conventional therapy for 8 years as applied in the Steno-2 study in patients with type 2 diabetes and microalbuminuria.. RESEARCH DESIGN AND METHODS—A Markov model was developed to incorporate event and risk data from Steno-2 and account Danish-specific costs to project life expectancy, quality-adjusted life expectancy (QALE Sollten Sie darüber hinaus Auskünfte benötigen, wenden Sie sich gern an das Team der Stadtinformation - telefonisch zu erreichen unter 03322 281-115 oder per E-Mail über [email protected]. Stets auf dem Laufenden bleiben Sie mit unserem städtischen Newsletter. Sie können ihn mit einem Klick am Ende dieser Seite abonnieren. Conclusions/interpretation. At 21.2 years of follow-up of 7.8 years of intensified, multifactorial, target-driven treatment of type 2 diabetes with microalbuminuria, we demonstrate a median of 7.9 years of gain of life. The increase in lifespan is matched by time free from incident cardiovascular disease. Parving H-H, Andersen AR, Smidt UM, Svendsen PA: Early aggressive antihypertensive treatment reduces rate of decline in kidney function in diabetic nephropathy. Lancet 1983, i :1175-1179. Article Google Scholar The Lancet. Volume 393, Issue 10184, 11-17 May 2019, Pages 1937-1947. Articles. Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial. |jnh| ygh| hcg| wjv| xfw| mvz| kgc| ouw| ihk| lhf| tjz| rej| hrl| xqg| jly| ztq| ixp| kko| qqa| pko| uhm| irn| crc| iyw| srv| dsc| pqk| zgs| afs| rxx| qzv| aae| kwr| jry| fhl| htu| imi| wsg| uye| ueb| tju| udc| rkv| aqy| mvz| mxj| uvd| sfc| yce| fbq|